From the North (Little River 2 hrs, N. Myrtle Beach 1½ hr, Myrtle Beach 1 hr, Surfside 50 min, Garden City 40 min, Murrells Inlet 30 min, Litchfield Beach 35 min, Litchfield 30 min, Pawleys Island 30 min, Pawleys Mainland 20 min, Debordieu 20 min): South on Hwy. 17 across the bridges into Georgetown. Drive 1 mile and turn right at the traffic light diagonally onto Black River Road. Drive past the hospital. Merge into Hwy. 701 and continue north for 1.5 miles. At the sign "Black River Outdoors Center & Expeditions", turn left onto Garden Ave.

From the North (Conway 45 min): South on Hwy. 701. South of Hwy. 51 merge, continue for 1 mile. At the sign "Black River Outdoors Center & Expeditions", turn right onto Garden Ave.

From the South (Charleston 1½+ hr, Isle of Palms 1½ hr, Mt. Pleasant 1¼ hr): North on Hwy. 17 into Georgetown. At the intersection of Hwys. 17, 701, and 521, continue north on Hwy. 701 for 3 miles (towards Conway). At the sign "Black River Outdoors Center & Expeditions", turn left onto Garden Ave.

From the West (Florence 1¼ hr): South on Hwy. 41. East on Hwy. 51. South on Hwy. 701 for 1 mile. At the sign "Black River Outdoors Center & Expeditions", turn right onto Garden Ave.

From the West (Charlotte 3½+ hr, Columbia 2½+ hr, Andrews 30 min): East on Hwy. 521. At the intersection of Hwys. 17, 701, and 521, turn left onto Hwy. 701 for 3 miles (towards Conway). At the sign "Black River Outdoors Center & Expeditions", turn left onto Garden Ave.